TILDREN FOR HORSE 500MG INJECTION

Tildren for Horses 500mg Injection

Tildren for Horses 500MG INJECTION As veterinarians, we are frequently asked about products to treat chronic conditions, subtle lameness or lameness that has not responded to other therapies. One of the most exciting products to come along in the last few years is Tildren.

Tildren for Horses 500mg Injection Treatment is a medication that has allowed us to offer a novel therapy for some of the most chronic causes of lameness that are often unresponsive to other therapies

How does it work?

Tildren for Horses 500mg Injection Treatment, or Tiludronate for all you pharmacology buffs, is a non-nitrogen containing bisphosphonate.

The bisphosphonates are a class of drug that work at the cellular level to slow down or prevent bone loss.  Bone is constantly changing and remodeling based on the forces applied to it. Osteoclasts are specialized bone cells which resorb bone, while osteoblasts are bone cells which serve to lay down new bone, a process known as mineralization. Tildren is thought to regulate bone remodeling by reducing the activity of osteoclasts while increasing osteoblastic activity.  Bone loss is reduced,

in the maintenance of or increase in bone density and strength.   Tildren was first used in human medicine for treating diseases that cause bone loss such as osteoporosis and Paget’s disease.  Other bisphosphonate drugs include Fosamax, Boniva, Actonel and Reclast.  In horses, Tildren has been studied for treatment of navicular disease, osteoarthritis and lesions of the thoracolumbar vertebral column.